Synthesis and evaluation as irreversible glycosidase inhibitors of mono- and oligo(glycosylthio)benzoquinones

Article abstract of DOI:10.1002/hlca.19940770319

The mono(glucosylthio)hydroquinone 2 was prepared by S-glycosidation of 2-mercaptobenzene-1,4-diol and by addition of the acetylated 1-thioglucose 3 to benzo-1,4-quinone (Scheme 1). The second, higher yielding procedure was adopted for the preparation of