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A Novel Synthesis of K-13

DOI: 10.1016/0040-4039(94)85322-3

Source and publish data:

Tetrahedron Letters p. 7391 - 7394 (1994)

Update date:2022-08-02

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Authors:

Beugelmans, ReneBeugelmans, Rene

Bigot, AntonyBigot, Antony

Zhu, JiepingZhu, Jieping

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Article abstract of DOI:10.1016/0040-4039(94)85322-3

A new and concise synthesis of 17-membered macrocyclic tripeptide K-13 is achieved featuring intramolecular SNAr reaction as a key step.

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Full text of DOI:10.1016/0040-4039(94)85322-3

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Product name:(S)-2-[(S)-2-[(S)-2-tert-Butoxycarbonylamino-3-(4-hydroxy-phenyl)-propionylamino]-3-(4-methoxy-phenyl)-propionylamino]-3-(3-fluoro-4-nitro-phenyl)-propionic acid methyl ester

Cas No:160247-88-1

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