Ketalised α- and β-lithiated α,β-unsaturated ketones: New masked acylvinyl anion equivalents

Article abstract of DOI:10.1016/S0040-4020(97)00187-7

The reaction of chloroketals 1, 5 and 10 with an excess of lithium powder and a catalytic amount of DTBB (4-5%) in THF at -78 or -90°C leads to the corresponding functionalised organolithium compounds 2, 6 and 11, respectively, resulting from a chlorine/l