Synthesis of Functionalized Furopyridines via the Pd-catalyzed Coupling of Acetylenes to Iodopyridones. Preparation of a Key Intermediate to a New HIV Protease Inhibitor L-754,394.

DOI: 10.1016/S0040-4039(00)78541-8

Source and publish data:

Tetrahedron Letters p. 9355 - 9358 (1994)

Update date:2022-09-26

Topics:

Authors:

Houpis, Ioannis N.

Choi, W. B.

Reider, P. J.

Molina, Audrey

Churchill, Hywyn

et al. et al.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)78541-8

The synthesis of 1 was accomplished in 55percent overall yield via the Pd-catalyzed coupling of 3 and 4 followed by Cu-catalyzed cyclization of the resulting intermediate 2.

Full text of DOI:10.1016/S0040-4039(00)78541-8

Products guided by the article

Product name:Furo[2,3-b]pyridine-5-carboxylic acid, ethyl ester

Cas No:160729-90-8

R&D Labs maybe for 160729-90-8

hangzhou verychem science and technology co.ltd

website:http://www.verypharm.com

Contact:+86-571-88162785; 88162786

Address:F1502, 753 Shenhua road, Hangzhou, China
Shenyang Mole pharmaceutical Technology Development Co.,Ltd

Contact:+86-24-31204918/13889278616

Address:No.44, wanliutang road, shenhe District of Shenyang
Jurong Huaheng Natural Biological Products Factory

website:http://www.risebiochem.com

Contact:+86-13921007726

Address:Chuncheng town,Jurong city,Jiangsu province,China
Jinan Trio PharmaTech Co., Ltd

Contact:86-531-88811783；+(0)13153010282

Address:2766 Yingxiu Road, Jinan High-Tech Zone, China
Sichuan WeiKeqi Biological Technology Co., Ltd.

website:https://www.weikeqi-biotech.com/en

Contact:86-028-81700200

Address:sichuan Chengdu Qingjiang Zhonglu 63号

Relevant to this article

Direct Free-Radical Substitutions on Allyl and Vinyl Halides Using Alkyl Halides/Hexabutylditin

Doi:10.1016/S0040-4039(00)93373-2
(1993)
Synthesis, structure and catalytic activity of low-spin dicyano iron(III) complexes of N,N′-bis(quinolyl)malonamide derivatives

Doi:10.1016/j.ica.2004.01.019
(2004)
Doi:10.1021/om00074a005
(1983)
Phenylene-bridged β-Ketoiminate Dilanthanide Aryloxides: Synthesis, Structure, and Catalytic Activity for Addition of Amines to Carbodiimides

Doi:10.1002/zaac.201500047
(2015)
N,N,N',N'-tetramethylmethanediamine, efficient reagent for thioles aminomethylation

Doi:10.1134/S1070428012020042
(2012)
Doi:10.1021/ja00477a075
(1978)

Article Doi