Tetrahedron p. 4889 - 4898 (1998)
Update date:2022-08-03
Topics:
Ly, Thi-My
Laso, Nieves M.
Zard, Samir Z.
A variety of 3-aryl substituted oxindoles can be rapidly constructed by treatment of a suitable 2,2-dimethoxy arylacetanilide, with titanium tetrachloride or boron trifluoride etherate; the synthesis of the precursors hinges on a powerful reaction between arylacetic acids and thionyl chloride.
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