
Tetrahedron Letters p. 6843 - 6846 (1994)
Update date:2022-08-02
Topics:
Chordia, Mahendra D.
Chaudhary, Ashok G.
Kingston, David G. I.
Jiang, Yuan Qing
Hamel, Ernest
4-Deacetoxypaclitaxel (9) has been prepared in seven steps from paclitaxel (Taxol<*>).It is significantly less active than paclitaxel in tubulin-assembly and cytotoxicity bioassays.
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Doi:10.1002/jps.2600670443
(1978)Doi:10.1248/cpb.13.1363
(1965)Doi:10.1007/s007060200026
(2002)Doi:10.1021/jo0257039
(2002)Doi:10.1002/jms.185
(2001)Doi:10.1021/jo01023a027
(1965)