Russian Chemical Bulletin p. 2201 - 2204 (1998)
Update date:2022-08-02
Topics:
Luk'yanov
Ternikova
Reactions of N,N-bis(chloromethyl)amides with N,N′-diacyl derivatives of ethylenediamine (or o-phenylenediamine) result in formation of the corresponding 1,3,5-triacylated perhydro-1,3,5-triazepines (or their benzoanalogs) or 1,3-diacylated imidazolidines (or their benzoanalogs). Reactions of N,N-bis(chloromethyl)amides with N,N′-ditosylated trimethylene-diamine occur in a similar way. The direction of the reactions depends on the type of the acyl substituents and the strength of the bases.
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