Conformationally restrained analogs of sympathomimetic catecholamines. Synthesis and adrenergic activity of tetrahydrobenzocycloheptene derivatives

DOI: 10.1016/0223-5234(94)90133-3

Source and publish data:

European Journal of Medicinal Chemistry p. 753 - 760 (1994)

Update date:2022-08-03

Topics:

Authors:

Macchia Macchia

Breschi Breschi

Gentili Gentili

Lapucci Lapucci

Macchia Macchia

Manera Manera

Martinelli

Martinotti

Nencetti

Nieri Nieri

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0223-5234(94)90133-3

The tetrahydrobenzocycloheptene analogs 7-10 of norepinephrine (NE, 1) and isoproterenol (ISO, 2) were synthesized and tested for their α- and β-adrenergic properties by means of functional tests on isolated preparations. The conformational profile of 7 w

Full text of DOI:10.1016/0223-5234(94)90133-3

Products guided by the article

Product name:1,2-dibenzyloxy-5-(aminomethyl)-6,7,8,9-tetrahydrobenzocyclohepten-5-ol

Cas No:160848-98-6

R&D Labs maybe for 160848-98-6

Jintan Jinnuo Chemical Co., Ltd.

Contact:+86-519-80199901

Address:Room 1804, Building 1, Huacheng Business Plaza, Jintan, Jiangsu, China
Hangzhou Taiyan Trading Co., Ltd(expird)

Contact:+86-13777583958

Address:NO.63, Xingyi Street, Xihu District, Hangzhou, Zhejiang, China
Hangzhou Yingshanhua Pigment Chemicals Co.,Ltd.

Contact:+86-0150-58101658

Address:Nanyang Economic DevelopmentZong,Xiaoshan,Hangzhou,China
YingYing Pharmaceutical Co.,Ltd

Contact:86-18854126208

Address:55#, yingxiongshan road
Suzhou Tianma Specialty Chemicals Co.,Ltd

Contact:+86-512-68090577

Address:#199, Huayuan Rd, Mudu, Suzhou, Jiangsu, CHINA

Relevant to this article

Unprecedented calcium metalla-macrocycle having phosphinoselenoic amide and diphenylphosphinate in the coordination sphere

Doi:10.1002/zaac.201300492
(2014)
Imine allylations by allylic trichlorotins derived from α,α-diisopropylhomoallylic alcohols with tin(II) chloride and N-chlorosuccinimide

Doi:10.1055/s-2002-35581
(2002)
Asymmetric Synthesis of Protected Cyclohexenylamines and Cyclohexenols by Rhodium-Catalyzed [2+2+2] Cycloaddition

Doi:10.1002/anie.201608952
(2016)
Synthesis of C3-substituted enantiopure 2-(p-tolylsulfinyl)-furans: The sulfoxide group as a chiral inductor for furan dienes as precursors of a wide variety of chiral intermediates

Doi:10.1016/j.tetasy.2014.03.013
(2014)
α-Arylation of Silyl Enol Ethers via Rhodium(III)-Catalyzed C-H Functionalization

Doi:10.1021/acscatal.9b05622
(2020)
Synthesis of heterocycles based on rhodium-catalyzed C-H amination

Doi:10.1055/s-0033-1340159
(2014)

Article Doi