Conformationally restrained analogs of sympathomimetic catecholamines. Synthesis and adrenergic activity of tetrahydrobenzocycloheptene derivatives

DOI: 10.1016/0223-5234(94)90133-3

Source and publish data:

European Journal of Medicinal Chemistry p. 753 - 760 (1994)

Update date:2022-08-03

Topics:

Authors:

Macchia Macchia

Breschi Breschi

Gentili Gentili

Lapucci Lapucci

Macchia Macchia

Manera Manera

Martinelli

Martinotti

Nencetti

Nieri Nieri

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0223-5234(94)90133-3

The tetrahydrobenzocycloheptene analogs 7-10 of norepinephrine (NE, 1) and isoproterenol (ISO, 2) were synthesized and tested for their α- and β-adrenergic properties by means of functional tests on isolated preparations. The conformational profile of 7 w

Full text of DOI:10.1016/0223-5234(94)90133-3

Products guided by the article

Product name:1,2-dibenzyloxy-5-(aminomethyl)-6,7,8,9-tetrahydrobenzocyclohepten-5-ol

Cas No:160848-98-6

R&D Labs maybe for 160848-98-6

Shanghai Taibao Pharmaceutical Technology Co., Ltd(expird)

Contact:021-52217366

Address:shanghai
Evergreen Chemical Industry Ltd.

Contact:86-553-4918210

Address:6#2-602 Wanhaobailing
NINGBO YINZHOU PRECISE COLOR CO.,LTD.

Contact:86-574-88139809 86-574-83033159

Address:Qiming Road,Yinzhou,Ningbo,China
Luojiang Chenming Biological Products Co

Contact:+86 15000297032

Address:GROUP NO.4, HE SHENG VILLAGE, PANLONG TOWN,
Zhengzhou Minzhong Pharmaceutical Co.,ltd

Contact:0086-371-65797115

Address:15/F,Jiangshan Bldg, NO.126 Huanghe Road,Zhengzhou, China

Relevant to this article

Unprecedented calcium metalla-macrocycle having phosphinoselenoic amide and diphenylphosphinate in the coordination sphere

Doi:10.1002/zaac.201300492
(2014)
Imine allylations by allylic trichlorotins derived from α,α-diisopropylhomoallylic alcohols with tin(II) chloride and N-chlorosuccinimide

Doi:10.1055/s-2002-35581
(2002)
Asymmetric Synthesis of Protected Cyclohexenylamines and Cyclohexenols by Rhodium-Catalyzed [2+2+2] Cycloaddition

Doi:10.1002/anie.201608952
(2016)
Synthesis of C3-substituted enantiopure 2-(p-tolylsulfinyl)-furans: The sulfoxide group as a chiral inductor for furan dienes as precursors of a wide variety of chiral intermediates

Doi:10.1016/j.tetasy.2014.03.013
(2014)
α-Arylation of Silyl Enol Ethers via Rhodium(III)-Catalyzed C-H Functionalization

Doi:10.1021/acscatal.9b05622
(2020)
Synthesis of heterocycles based on rhodium-catalyzed C-H amination

Doi:10.1055/s-0033-1340159
(2014)

Article Doi