Conformationally restrained analogs of sympathomimetic catecholamines. Synthesis and adrenergic activity of tetrahydrobenzocycloheptene derivatives

DOI: 10.1016/0223-5234(94)90133-3

Source and publish data:

European Journal of Medicinal Chemistry p. 753 - 760 (1994)

Update date:2022-08-03

Topics:

Authors:

Macchia Macchia

Breschi Breschi

Gentili Gentili

Lapucci Lapucci

Macchia Macchia

Manera Manera

Martinelli

Martinotti

Nencetti

Nieri Nieri

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0223-5234(94)90133-3

The tetrahydrobenzocycloheptene analogs 7-10 of norepinephrine (NE, 1) and isoproterenol (ISO, 2) were synthesized and tested for their α- and β-adrenergic properties by means of functional tests on isolated preparations. The conformational profile of 7 w

Full text of DOI:10.1016/0223-5234(94)90133-3

Products guided by the article

Product name:1,2-dibenzyloxy-5-(aminomethyl)-6,7,8,9-tetrahydrobenzocyclohepten-5-ol

Cas No:160848-98-6

R&D Labs maybe for 160848-98-6

Daqing New Century Fine Chemical Co., Ltd.(expird)

Contact:010-57126694

Address:No.39, jinxing cun, honggang district
HuiFeiChem PharmaTech Co.Ltd

Contact:0510-85393305

Address:1619 Huishan Avenue, Huishan District, Wuxi,
Hybio Pharmaceutica Co.,Ltd

Contact:+86 755 26588093

Address:No.9 Linkong West Street, Hengdian Street, Huangpi District, Wuhan City, China.
MiHecb Bio-Tech Co., Ltd.

Contact:+86-0592 5353131

Address:No.56 Guani Road Software Park 2,Siming District
Hebei Maison Chemical Co.,Ltd

website:http://www.maisonchem.com.cn

Contact:0086-311-83833777

Address:Leitou industrial district, xinji, shijiazhuang city, hebei province,

Relevant to this article

Unprecedented calcium metalla-macrocycle having phosphinoselenoic amide and diphenylphosphinate in the coordination sphere

Doi:10.1002/zaac.201300492
(2014)
Imine allylations by allylic trichlorotins derived from α,α-diisopropylhomoallylic alcohols with tin(II) chloride and N-chlorosuccinimide

Doi:10.1055/s-2002-35581
(2002)
Asymmetric Synthesis of Protected Cyclohexenylamines and Cyclohexenols by Rhodium-Catalyzed [2+2+2] Cycloaddition

Doi:10.1002/anie.201608952
(2016)
Synthesis of C3-substituted enantiopure 2-(p-tolylsulfinyl)-furans: The sulfoxide group as a chiral inductor for furan dienes as precursors of a wide variety of chiral intermediates

Doi:10.1016/j.tetasy.2014.03.013
(2014)
α-Arylation of Silyl Enol Ethers via Rhodium(III)-Catalyzed C-H Functionalization

Doi:10.1021/acscatal.9b05622
(2020)
Synthesis of heterocycles based on rhodium-catalyzed C-H amination

Doi:10.1055/s-0033-1340159
(2014)

Article Doi