Journal of the American Chemical Society p. 11113 - 11123 (1995)
Update date:2022-07-30
Topics:
Smith III, Amos B.
Hirschmann, Ralph
Pasternak, Alexander
Guzman, Mark C.
Yokoyama, Akihisa
Sprengeler, Paul A.
Darke, Paul L.
Emini, Emilio A.
Schleif, William A.
Pyrrolinone-based peptidomimetics, the first mimics of β-strands, are potent inhibitors of HIV-1 protease. Importantly, the bis(pyrrolinones) described herein proved to be more active in cellular antiviral assays compared with an analogous peptide-derived
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(1995)