Intramolecular Amidoalkylation of Aromatics III. Synthesis of Conformationally Restricted Bridged Peptide Analogues of Phe-Gly

DOI: 10.1016/S0040-4020(01)89269-3

Source and publish data:

Tetrahedron p. 10771 - 10782 (1994)

Update date:2022-08-03

Topics: Synthesis Intramolecular Aromatics Conformationally

Authors:

Rabi-Barakay, Amal

Ben-Ishai, Dov

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Article abstract of DOI:10.1016/S0040-4020(01)89269-3

Derivatives of the Phe-α-methoxyglycine (4) were prepared and found to undergo stereospecific intramolecular amidoalkylation to give derivatives of 4-amino-2-benzazepin-3-one-1-carboxylic acid 5 (ABZC).The cyclic compounds 5a-g are conformationally restri

Full text of DOI:10.1016/S0040-4020(01)89269-3

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