Synthesis of iodo-aryl-azido adenosine analogs as affinity ligands for adenylyl cyclase

Article abstract of DOI:10.1080/15257779408010676

Potential affinity probes for adenylyl cyclase were synthesized that take advantage of the enzyme's sensitivity to 'P'-site-mediated inhibition by 2',5'-dideoxyadenosine analogs and its tolerance for large 3'-ribose substitutions. We report the synthesis

Full text of DOI:10.1080/15257779408010676

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Nucleosides and Nucleotides
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Synthesis of Iodo-aryl-azido Adenosine
Analogs as Affinity Ligands for Adenylyl
Cyclase
Ilana Shoshani a , Howard Qiu b , Francis Johnson b & Roger A.
Johnson a
a Department of Physiology and Biophysics , School of Medicine,
Health Sciences Center , Stony Brook, Stony Brook, New York,
11794-8661, U.S.A.
b Department of Chemistry , State University of New York , Stony
Brook, Stony Brook, New York, 11794-8661, U.S.A.
Published online: 24 Sep 2006.
To cite this article: Ilana Shoshani , Howard Qiu , Francis Johnson & Roger A. Johnson (1994)
Synthesis of Iodo-aryl-azido Adenosine Analogs as Affinity Ligands for Adenylyl Cyclase, Nucleosides
and Nucleotides, 13:9, 1977-1989, DOI: 10.1080/15257779408010676
To link to this article: http://dx.doi.org/10.1080/15257779408010676
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