A NOVEL DIASTEREOSELECTIVE SYNTHESIS OF CHIRAL, NON-RACEMIC UNSYMMETRICAL THIOACETALS USING SILICON-INDUCED PUMMERER-TYPE REACTION

Article abstract of DOI:10.1016/0040-4039(94)02178-E

Chiral, non-racemic sulfoxides were reacted with thiols and BSA in the presence of a catalytic amount of TMSOTf in MeCN at rt overnight to give the corresponding chiral, non-racemic anti-thioacetals with high diastereoselectivity.