The synthesis of novel transition state analogues related to imidazole and purine nucleotides involved in the de novo biosynthesis of purines

Article abstract of DOI:10.1080/15257779508012383

5-Amino-4-sulphonamidoimidazole ribofuranosyl nucleosides and a related imidazothiadiazine dioxide nucleoside have been synthesized as potential inhibitors of enzymes involved in the de novo biosynthesis of purine nucleotides.

Full text of DOI:10.1080/15257779508012383

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The Synthesis of Novel Transition State
Analogues Related to Imidazole and
Purine Nucleotides Involved in the De
novo Biosynthesis of Purines
A. Scott Frame a , Richard H. Wightman a & G. Mackenzie b
a Department of Chemistry , Heriot-Watt University , Edinburgh,
EH14 4AS, UK.
b School of Chemistry, University of Hull , Hull, HU6 7RX, UK.
Published online: 16 Feb 2007.
To cite this article: A. Scott Frame , Richard H. Wightman & G. Mackenzie (1995) The Synthesis of
Novel Transition State Analogues Related to Imidazole and Purine Nucleotides Involved in the De novo
Biosynthesis of Purines, Nucleosides and Nucleotides, 14:3-5, 363-366
To link to this article: http://dx.doi.org/10.1080/15257779508012383
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