Fluorine for hydroxy substitution in biogenic amines: Asymmetric synthesis and biological evaluation of fluorine-18-labeled β-fluorophenylalkylamines as model systems

DOI: 10.1021/jm00005a008

Source and publish data:

Journal of Medicinal Chemistry p. 810 - 815 (1995)

Update date:2022-08-05

Topics:

Authors:

Van Dort

Jung Jung

Sherman Sherman

Kilbourn

Wieland Wieland

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00005a008

This work explores the biomimetic potential of [¹⁸F]fluorine for hydroxy substitution in β-phenethanolamines as a possible strategy for developing radiotracers for in vivo imaging. Stereospecific syntheses of the two model compounds (1R,2S)-1-[

Full text of DOI:10.1021/jm00005a008

Products guided by the article

Product name:1-fluoro-1-deoxyephedrine

Cas No:161403-39-0

R&D Labs maybe for 161403-39-0

ZHEJIANG SYNOSE TECH CO.,LTD.

website:https://www.synose.com/

Contact:86-579-82275537

Address:No.1958 Liyu Road , jinhua,zhejiang,China
Kunshan Yalong Trading Co,.Ltd

Contact:86-512-57621185

Address:805-807 Room Hongqiao Mansion ,1088 West Qianjin Road, Kunshan, Jiangsu，China
Basilea Pharmaceutica China Ltd.

Contact:+86-513-82198075

Address:No.638 Xiushan Road(East),Haimen, Jiangsu 226100, P.R.China
Yixing Bluwat Chemicals Co., Ltd.

Contact:+86 510 87821568

Address:Yongan Road, Yixing Chemical Industrial Park, Yixing, Jiangsu, China
Hangzhou Yingshanhua Pigment Chemicals Co.,Ltd.

Contact:+86-0150-58101658

Address:Nanyang Economic DevelopmentZong,Xiaoshan,Hangzhou,China

Relevant to this article

Synthesis of homochiral dihydroxy-4-nitroisoxazolines via one-pot asymmetric dihydroxylation-reduction

Doi:10.1021/ol800397z
(2008)
Diastereoselective synthesis of highly functionalized fluoroalkene dipeptide isosteres and its application to Fmoc-based solid-phase synthesis of a cyclic pentapeptide mimetic

Doi:10.1016/j.tet.2008.02.076
(2008)
Synthesis, antifungal and cytotoxic activities of 2-aryl-3-((piperidin-1- yl)ethyl)thiazolidinones

Doi:10.1016/j.ejmech.2013.03.030
(2013)
Diastereofacial selectivity in aldol-type condensation induced by optically pure α-sulfinyl acetate with α-substituted aldehydes

Doi:10.1016/j.tetlet.2008.02.033
(2008)
A novel synthesis of α-azidocinnamates, α-azido-α,β-unsaturated ketones and β-azidostyrenes mediated by cerium(IV) ammonium nitrate

Doi:10.1016/S0040-4039(00)00350-6
(2000)
Synthesis of new bis(2-[1,8]naphthyridinyl) bridging ligands with?multidentate binding sites

Doi:10.1016/j.tet.2008.02.017
(2008)

Article Doi