Fluorine for hydroxy substitution in biogenic amines: Asymmetric synthesis and biological evaluation of fluorine-18-labeled β-fluorophenylalkylamines as model systems

DOI: 10.1021/jm00005a008

Source and publish data:

Journal of Medicinal Chemistry p. 810 - 815 (1995)

Update date:2022-08-05

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Authors:

Van Dort

Jung Jung

Sherman Sherman

Kilbourn

Wieland Wieland

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Article abstract of DOI:10.1021/jm00005a008

This work explores the biomimetic potential of [¹⁸F]fluorine for hydroxy substitution in β-phenethanolamines as a possible strategy for developing radiotracers for in vivo imaging. Stereospecific syntheses of the two model compounds (1R,2S)-1-[

Full text of DOI:10.1021/jm00005a008

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