Tetrahedron Letters p. 8299 - 8302 (1994)
Update date:2022-09-26
Topics:
Gala, Dinesh
DiBenedetto, Donald J.
A new, mild method for the direct conversion of chiral aryl epoxides to hydroxy-protected chiral α-hydroxy aryl ketones with complete retention of the chiral center and good regioselectivity has been established. An application of this new reaction to the synthesis of antifungal Sch 42427/SM 9164 is also described.
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Doi:10.1021/jm00309a009
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