Synthesis of 2,4-diaza-4-deoxypodophyllotoxin, a new analogue of podophyllotoxin possessing antitumour activity

DOI: 10.1039/c39950000049

Source and publish data:

Journal of the Chemical Society. Chemical communications p. 49 - 50 (1995)

Update date:2022-08-03

Topics:

Authors:

Hitotsuyanagi

Naka Naka

Yamagami

Fujii Fujii

Tahara Tahara

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1039/c39950000049

2,4-Diaza-4-deoxypodophyllotoxin 4 and its cis analogue 14 are synthesised stereoselectively from 3,4-methylenedioxyaniline 5, and show significant activity against vincristine-resistant P-388 leukaemia in vivo.

Full text of DOI:10.1039/c39950000049

View Article Online / Journal Homepage / Table of Contents for this issue

View Article Online

Products guided by the article

Product name:(6-Benzylamino-benzo[1,3]dioxol-5-yl)-(3,4,5-trimethoxy-phenyl)-methanol

Cas No:161616-63-3

R&D Labs maybe for 161616-63-3

Wuhan Silworld Chemical Co.,Ltd

website:http://www.silworldchemical.com

Contact:+86-27-85613400

Address:No.198 jiangjun Road, Wuhan,China 430033
Hunan Haili Chemical Industry Co.,Ltd.

Contact:+86-731-85521860

Address:No.251, 2nd Section, Furong Road, Changsha,Hunan,China
Dragon Chemical Co., Ltd.

Contact:0571-

Address:zhejing
Chengdu Biopurify Phytochemicals Ltd.

website:http://www.phytopurify.com

Contact:+86-28-82633397

Address:2F,No.11 Building,No.388 Rongtaidadao CNSTP,Wenjiang Zone,Chengdu,Sichuan, China
HAORUI ENTERPRISES LLC

Contact:(1) 206-3550089

Address:5115 NE 8TH PL, Renton, WA 98059 USA

Relevant to this article

Access to P- and Axially Chiral Biaryl Phosphine Oxides by Enantioselective Cp^xIr^III-Catalyzed C?H Arylations

Doi:10.1002/anie.201807749
(2018)
Ortho-Metallated triphenylphosphine chalcogenide complexes of platinum and palladium: Synthesis and catalytic activity

Doi:10.1039/c4dt01236d
(2014)
Agents combining thromboxane receptor antagonism with thromboxane synthase inhibition: [[[2-(1H-imidazol-1-yl)ethylidene]amino]oxy]alkanoic acids

Doi:10.1021/jm00047a016
(1994)
Phosphorylated hydrazines and aldehydes as precursors of phosphorus-containing multimacrocycles

Doi:10.1021/ja00111a007
(1995)
Synthesis of scutellarein derivatives to increase biological activity and water solubility

Doi:10.1016/j.bmc.2015.09.047
(2015)
Synthesis and characterisation of unsymmetrical Zr(iv) amine tris(phenolate) complexes and their application in ROP of rac-LA

Doi:10.1039/c4dt01260g
(2014)

Article Doi