An unexpected reversal of stereochemistry in a modification of the Rychnovsky cyanohydrin alkylation

DOI: 10.1016/S0040-4039(00)78353-5

Source and publish data:

Tetrahedron Letters p. 7601 - 7604 (1994)

Update date:2022-08-04

Topics:

Authors:

Brzezinski, Linda Joy

Levy, Dinah D.

Leahy, James W.

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Article abstract of DOI:10.1016/S0040-4039(00)78353-5

Alkylation of cyanohydrin 1,3-acetonides with unsaturated substitution at the 2-position is described. The stereochemistry of the products obtained from this reaction was opposite to that anticipated.

Full text of DOI:10.1016/S0040-4039(00)78353-5

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