Radical Cyclization of Bromomethyldimethylsilyl Propargyl Ethers; Synthesis of a Carbocyclic Core of Steroid Skeleton by a Tandem Radical Cyclization

Article abstract of DOI:10.1016/S0040-4039(00)78447-4

Homoallyl radical intermediates, generated from the cyclization of bromomethyl-dimethylsilyl propargyl ethers, have been trapped intramolecularly by a double bond in a 6-exo-trig radical process.In that instance, a carbocyclic core of steroid skeleton has