Benzyloxy(diisopropylamino)methylphosphine: A powerful reagent for the synthesis of methylphosphonopeptides

DOI: 10.1055/s-1995-3848

Source and publish data:

Synthesis p. 97 - 100 (1995)

Update date:2022-07-29

Topics:

Authors:

Wijkmans

Ottenheim

Kuyl-Yeheskiely

Van Der Marel

Bloemhoff

Van Boom

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Article abstract of DOI:10.1055/s-1995-3848

The preparation of methylphosphonylated amino acids and peptides using O,O-bis(benzotriazol-1-yl) methylphosphonate and the favourable novel reagent benzyloxy(diisopropylamino)methylphosphine [benzyl (N,N-diisopropyl)methylphosphonamidite] is described.

Full text of DOI:10.1055/s-1995-3848

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