Synthesis and application of N-Boc-L-2-amino-4-(diethylphosphono)4,4-difluorobutanoic acid for solid-phase synthesis of nonhydrolyzable phosphoserine peptide analogues

Article abstract of DOI:10.1016/0040-4039(94)02374-K

Synthesis of N-Boc-L-2-amino-4-(diethylphosphono)-4,4-difluorobutanoic acid is reported. This analogue was utilized for the solid-phase synthesis of a peptide containing a nonhydrolyzable phosphoserine mimetic.