Synthesis and application of N-Boc-L-2-amino-4-(diethylphosphono)4,4-difluorobutanoic acid for solid-phase synthesis of nonhydrolyzable phosphoserine peptide analogues

DOI: 10.1016/0040-4039(94)02374-K

Source and publish data:

Tetrahedron Letters p. 927 - 930 (1995)

Update date:2022-08-02

Topics:

Authors:

Otaka Otaka

Miyoshi Miyoshi

Burke Jr.

Roller Roller

Kubota Kubota

Tamamura

Fujii Fujii

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Article abstract of DOI:10.1016/0040-4039(94)02374-K

Synthesis of N-Boc-L-2-amino-4-(diethylphosphono)-4,4-difluorobutanoic acid is reported. This analogue was utilized for the solid-phase synthesis of a peptide containing a nonhydrolyzable phosphoserine mimetic.

Full text of DOI:10.1016/0040-4039(94)02374-K

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