Tetrahedron Letters p. 5661 - 5665 (1999)
Update date:2022-08-05
Topics:
Eckert, Jeffrey
Chan, Tze-Ming
Osterman, Rebecca M.
Lambert, Joseph B.
Gala, Dinesh
A mechanistic study of the simple sequential N-arylation of piperazine suggests that in an electron-withdrawing group (EWG) containing N-arylated piperazines, hydrogen bonding of the secondary amine hydrogen is important for its non-metal catalyzed conversion to N,N'-diaryl piperazines. A combination of synthetic experiments, molecular modeling, and NMR studies were carried out to test this hypothesis.
View MoreQuzhou Aokai Chemical Co., Ltd.
Contact:86-570-3032832
Address:NO.16 , Laodong Road,Quzhou City, Zhejiang Province,China
Allright GC (Jinan) Biotechnology Ltd.
website:https://www.argcbiotech.com/
Contact:86-18405413579-
Address: No.27566 of Jingshiroad, Huaiyin District, Jinan City(250011), Shandong Province, China.
Taimai Sanluck Pharmaceutical Co.,Ltd
Contact:86-592-7662921
Address:8D,No.186,Huarong Road,Huli,Xiamen,China
Changsha Yonta Industry Co., Ltd.
Contact:+ 86-731-8535 2228
Address:Rm.1717, North Bldg., No.368, East 2nd Ring Road(2nd Section)
Jinan Jinguilin Chemical Co.,Ltd
Contact:+86-531-81188412
Address:3rd floor of Torch Building, Huanyuan Rd, City of Jinan
Doi:10.1002/ejoc.201402460
(2014)Doi:10.1007/s11164-015-2112-4
(2016)Doi:10.1021/ja502824c
(2014)Doi:10.1002/pola.27223
(2014)Doi:10.1039/c4ra02174f
(2014)Doi:10.1016/0022-328X(94)05104-J
(1995)
