New efficient synthesis of thymidine cyclic 3′, 5′-phosphorofluoridate and its sulfur analogue via the phosphoroamidite route

Article abstract of DOI:10.1080/15257770008045459

We describe the convenient synthesis of thymidine cyclic 3′, 5′-phosphorofluoridate 6, which is superior to that previously reported. Our procedure is based on a sequence of reactions utilizing 3 as the key substrate. Similar sequence of reaction leads to

Full text of DOI:10.1080/15257770008045459

Nucleosides, Nucleotides and Nucleic Acids
ISSN: 1525-7770 (Print) 1532-2335 (Online) Journal homepage: http://www.tandfonline.com/loi/lncn20
New Efficient Synthesis of Thymidine Cyclic 3′, 5′-
Phosphorofluoridate and Its Sulfur Analogue via
the Phosphoroamidite Route
Wojciech Dąbkowski , Izabela Tworowska , Jan Michalski & Friedrich Cramer
To cite this article: Wojciech Dąbkowski , Izabela Tworowska , Jan Michalski & Friedrich Cramer
(2000) New Efficient Synthesis of Thymidine Cyclic 3′, 5′- Phosphorofluoridate and Its Sulfur
Analogue via the Phosphoroamidite Route, Nucleosides, Nucleotides and Nucleic Acids,
19:10-12, 1779-1785, DOI: 10.1080/15257770008045459
To link to this article: http://dx.doi.org/10.1080/15257770008045459
Published online: 17 Apr 2008.
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Date: 05 November 2015, At: 15:17