Tetrahedron Letters p. 1401 - 1404 (1995)
Update date:2022-07-30
Topics:
Lainton, Julia A. H.
Huffman, John W.
Martin, Billy R.
Compton, David R.
The design and synthesis of a series of 1-alkyl-3-(1-naphthoyl)pyrroles is described. Molecular modeling studies were employed to aid in the design of these compounds. During the course of the synthesis the Friedel-Crafts reactions of N-aryl sulfonyl pyrroles were reinvestigated. The title compounds (4) were subjected to pharmacological evaluation and the data obtained have enabled these pyrroles to be classified as cannabinoids.
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(1995)
