Novel potent and m2-selective antimuscarinic compounds which penetrate the blood-brain barrier

DOI: 10.1016/0223-5234(96)88210-9

Source and publish data:

European Journal of Medicinal Chemistry p. 61 - 70 (1995)

Update date:2022-08-03

Topics:

Authors:

Cohen, V. I.

Jin, B. Jin, B.

Gitler, M. S.

Cruz, R. A. de la

Boulay, S. F.

et al. et al.

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Article abstract of DOI:10.1016/0223-5234(96)88210-9

A series of 5-<<<(dialkylamino)alkyl>-1-phenyl>acetyl>-10,11-dihydro-5H-dibenzo<1,4>diazepin-11-ones 1 were prepared as potential m₂-selective ligands.The binding affinities and selectivities of these compounds for the muscarinic cholinerg

Full text of DOI:10.1016/0223-5234(96)88210-9

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Product name:5-{2-[4-(5-Bromo-pentyl)-phenyl]-acetyl}-5,10-dihydro-dibenzo[b,e][1,4]diazepin-11-one

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