Functionalized o-bis(chloromethyl)pyridines as precursors for pyridine o-quinodimethane analogues and their [4 + 2] cycloadducts

Article abstract of DOI:10.1016/0040-4039(95)00169-D

From oxazinones 4, precursors for pyridine o-quinodimethane analogues are made accessible via cycloaddition with 1,4-dichloro-2-butyne and propargyl chloride. Subsequent 1,4-elimination of the polyfunctional o-bis(chloromethyl)-pyridines affords both 2,3-