Design and synthesis of novel inhibitors of HIV-1 reverse transcriptase

DOI: 10.1021/jm00012a014

Source and publish data:

Journal of Medicinal Chemistry p. 2145 - 2151 (1995)

Update date:2022-08-06

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Authors:

Maruenda

Johnson Johnson

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Article abstract of DOI:10.1021/jm00012a014

A variety of N1-substituted pyrimido[5,4-f]benzo[1,4]thiazepines, 5, designed as conformationally constrained analogs of 1-[(2- hydroxyethoxy)methyl]-6-(phenylthio)thymine HEPT (1), were synthesized and evaluated for their inhibition of human immunodefici

Full text of DOI:10.1021/jm00012a014

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