Design and synthesis of novel inhibitors of HIV-1 reverse transcriptase

DOI: 10.1021/jm00012a014

Source and publish data:

Journal of Medicinal Chemistry p. 2145 - 2151 (1995)

Update date:2022-08-06

Topics:

Authors:

Maruenda

Johnson Johnson

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00012a014

A variety of N1-substituted pyrimido[5,4-f]benzo[1,4]thiazepines, 5, designed as conformationally constrained analogs of 1-[(2- hydroxyethoxy)methyl]-6-(phenylthio)thymine HEPT (1), were synthesized and evaluated for their inhibition of human immunodefici

Full text of DOI:10.1021/jm00012a014

Products guided by the article

Product name:6-<<2-(N-methylamino)phenyl>thio>uracil

Cas No:164029-06-5

R&D Labs maybe for 164029-06-5

Tianjin Pharmacn Medical Technology Co.,Ltd.

Contact:86-22-60122566ext.866(English),23359620

Address:Green Industrial Base, 6 Haitaifazhan Sixth Rd., Huayuan Industrial Area, Tianjin, 300384, China
xujianqiang

Contact:86-21-57725962

Address:shanghai
RongCheng K&S Chemical Co.,Ltd

Contact:0631-7336369

Address:rongcheng ,shandong province china
Anhui Eapearl Chemical Co., Ltd.

Contact:86-562-5858458

Address:358 South Huaihe Road
chemonlinephramacistdepot

Contact:86-607-68073220

Address:1 ave na road jiahua st

Relevant to this article

Tunable heptamethine-azo dye conjugate as an NIR fluorescent probe for the selective detection of mitochondrial glutathione over cysteine and homocysteine

Doi:10.1021/ja500962u
(2014)
Design, synthesis and biological evaluation of C(6)-modified celastrol derivatives as potential antitumor agents

Doi:10.3390/molecules190710177
(2014)
A novel domino synthesis of quinazolinediones by palladium-catalyzed double carbonylation

Doi:10.1002/chem.201403417
(2014)
(E)- and (Z)-4-ethynyl-4′-nitrostilbene

Doi:10.1107/S0108270196009845
(1996)
Anacardic acid derived salicylates are inhibitors or activators of lipoxygenases

Doi:10.1016/j.bmc.2012.06.019
(2012)
Synthesis of Acylhydrazido-Substituted Cephems. Design of Cephalosporin-Vinca Alkaloid Prodrugs: Substrates for an Antibody-Targeted Enzyme

Doi:10.1021/jo00034a027
(1992)

Article Doi