Synthesis of optically active macrocycles containing two 1,2,4-triazole subunits

Article abstract of DOI:10.1055/s-1994-25644

The stepwise synthesis of novel lipophilic, optically active macrocyclic crown ethers (S,S,S,S)-5,6,8 and 9, with four chiral centers of the same configuration and two 1,2,4-triazole subunits, starting from readily accessible chiral 3,5-disubstituted 1,2,