Chiral 2,3-disubstituted indolines from indoles and aldehydes by organocatalyzed tandem synthesis involving reduction by trichlorosilane

DOI: 10.1002/adsc.201301133

Source and publish data:

Advanced Synthesis and Catalysis p. 2224 - 2230 (2014)

Update date:2022-07-30

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Authors:

Chen, Lin

Wang, Chao

Zhou, Li

Sun, Jian

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Article abstract of DOI:10.1002/adsc.201301133

The organocatalytic trichlorosilane reduction system has been successfully utilized to develop a multi-step tandem approach for the easy preparation of chiral 2-methyl-3-alkylindolines starting from simple 2-methylindoles and aldehydes. A broad range of c

Full text of DOI:10.1002/adsc.201301133

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