Tetrahedron Letters p. 4985 - 4988 (1995)
Update date:2022-08-03
Topics:
Fitjer, Lutz
Schlotmann, Werner
Noltemeyer, Mathias
Cyclobutyl phenyl sulfide 2, cyclobutyl phenyl sulfoxide 3 and (SR)- cyclobutyl p-tolyl sulfoxide (SR)-8 have been synthesized and used for the spiroannelation of cyclopentanone. In the most effective sequence, lithiated 3 is added to ketones with formation of β-hydroxy sulfoxides 4a-g, which are ring enlarged and hydrolyzed to cyclopentanones 6a-e and sulfanylcyclopentene 6f, respectively, after reduction to β-hydroxy sulfides 5a-f. In an asymmetric version using (SR)-8, partial racemization during ring enlargement was observed.
View MoreMS( MAOSHENG )Chemical CO.,LTD
Contact:+86-519-82726678.82726378
Address:TAOXI INDUSTRY ZONE JINTAN
Contact:86-371-63655023
Address:No.85,jinshui road,zhengzhou,China
Changzhou LanXu Chemical Co.,ltd.(expird)
Contact:86-0519-86330911,13656129734,15261186386
Address:Room 524, Depart.Chemical, Changzhou Science and Eductaion town, Jiangsu, China;Factory: Haian Fine Chemical Industry Park,Nantong,Jiangsu,China
Shanghai Sunwise Chemical Co., Ltd
website:http://www.sunwisechem.com
Contact:86-021-33883180
Address:Room 10E, Building G, Westlink Center, No. 2337 Gudai Road, Minhang District, Shanghai, China PC: 201100
Guangzhou PI & PI Biotech Inc. Ltd.
Contact:+86-20-81716320
Address:Suite 501,198 Kaiyuan Ave.,Science City, Guangzhou,China
Doi:10.1002/adsc.200303219
(2004)Doi:10.1021/ja00240a019
(1987)Doi:10.1016/0040-4020(95)00428-B
(1995)Doi:10.1016/j.tetlet.2017.01.075
(2017)Doi:10.1002/poc.610080905
(1995)Doi:10.1016/0040-4039(95)01307-4
(1995)