Novel cytotoxic 3'-(tert-butyl) 3'-dephenyl analogs of paclitaxel and docetaxel

DOI: 10.1021/jm00019a012

Source and publish data:

Journal of Medicinal Chemistry p. 3821 - 3828 (1995)

Update date:2022-08-03

Topics:

Authors:

Ali Ali

Hoemann Hoemann

Aube Aube

Mitacher

Georg Georg

McCall McCall

Jayasinghe

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00019a012

3'-(tert-Butyl) 3'-dephenyl analogs of paclitaxel were synthesized from 10-deacetylbaccatin III and oxazolidinecarboxylic acid 7 followed by acylation of intermediate amines 10 and 11. Oxazolidinecarboxylic acid 7 was prepared in five steps and in good ov

Full text of DOI:10.1021/jm00019a012

Products guided by the article

Product name:3'-tert-butyl-10-deacetyl-N-debenzoyl-3'-dephenyl-7,10-bis<<(2,2,2-trichloroethyl)oxy>carbonyl>paclitaxel

Cas No:170241-01-7

R&D Labs maybe for 170241-01-7

Sinonine Industry Co.,Ltd

Contact:86+21-56421993

Address:3F,BUILDING 10,NO.2889 JINKE ROAD, SHANGHAI.
Hangzhou Zyter Biological & Chemical Technology Co., Ltd.

website:http://www.zyterpharm.com

Contact:+86-18858184290

Address:West Wenyi Road, Cangqian, Yuhang
Liao Cheng All Win Chemicals Co.,LTD

Contact:86+0635-2991582

Address:Room 402,Unit 1,No.27 building.Zhong tong shi dai haoyuan,liaocheng city,Shan dong Province.China
Jiangyin Tenghua Import&Export Co.,Ltd.

Contact:+86-510-86263875

Address:Room 402-B,9 Yanling Road, Jiangyin,Jiangsu, China
Pengchen New Material Technology Co., Ltd.

Contact:+86-512-63680537

Address:99.6 km of national road 318, Meiyan Community,Pingwang Town, Wujiang District, Suzhou 215225

Relevant to this article

Effects of hindrance in N-pyridyl imidazolylidenes coordinated to iridium on structure and catalysis

Doi:10.1021/om400758b
(2013)
Doi:10.1021/ja01006a060
(1968)
Configurational isomerization of push-pull thiazolidinone derivatives controlled by intermolecular and intramolecular RAHB: ¹H NMR dynamic investigation of concentration and temperature effects

Doi:10.1002/poc.700
(2004)
Palladium-catalysed stereoselective synthesis of 4-(diarylmethylidene)-3,4-dihydroisoquinolin-1(2: H)-ones: expedient access to 4-substituted isoquinolin-1(2 H)-ones and isoquinolines

Doi:10.1039/c7ob02788e
(2018)
Direct versatile route to conformationally constrained glutamate analogues

Doi:10.1039/a708429c
(1998)
Doi:10.1016/S0022-328X(00)94160-3
(1965)

Article Doi