Synthesis, structure and properties of 5,5-diphenyl-2,3,5,6-tetrahydroimidazo-[2,1b]-imidazoline-3,6-dione

Article abstract of DOI:10.1002/ardp.19953280608

Cyclization of N-[(5,5-diphenyl)-4-oxo-2-imidazolidinyl]glycine (3) yielded 5,5-diphenyl-2,3,5,6-tetrahydroimidazo[2,1-b]imidazoline-3,6-dione (6) or its acetyl derivative 5 depending on the method used. The stabilities of 5 and 6 in acidic or alkaline solutions were examined. The crystal structure of the hydrolysis products 7, 8 of 5 and 6 were solved by X-ray analysis.