Tetrahedron Letters p. 8693 - 8696 (1995)
Update date:2022-07-31
Topics:
Gilchrist
Graham
Coulton
The benzocarbapenem 1 has been prepared from ethyl indole-2-acetate by reduction, hydrolysis of the ester and cyclisation. The methyl substituted carbapenems 12, 13 and 14 have also been prepared. The hydrogenation of ethyl N-BOC-indole-2-propanoate 5 is diastereoselective.
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