Synthesis of chiral β-amino sulfides and β-amino thiols from α-amino acids

Article abstract of DOI:10.1016/0957-4166(95)00197-W

Bifurcated routes to two series of chiral secondary β-amino sulfides 5a-c and 11a-c have been developed from L-proline and (S)-phenylglycine, respectively. The developed methodology had also led to the synthesis of the tertiary β-amino thiol 7 and the primary β-amino sulfide 12 from L-proline and (S)-phenylglycine, respectively.