Asymmetric Synthesis of a Key Camptothecin Intermediate from 2-Fluoropyridine

DOI: 10.1016/0040-4039(95)01665-5

Source and publish data:

Tetrahedron Letters p. 7995 - 7998 (1995)

Update date:2022-08-05

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Authors:

Comins, Daniel L.

Saha, Jayanta K.

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Article abstract of DOI:10.1016/0040-4039(95)01665-5

The DE ring camptothecin intermediate II was prepared enantioselectively in six steps from 2-fluoropyridine using a pyridine "halogen-dance" reaction.

Full text of DOI:10.1016/0040-4039(95)01665-5

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