Asymmetric Synthesis of a Key Camptothecin Intermediate from 2-Fluoropyridine

DOI: 10.1016/0040-4039(95)01665-5

Source and publish data:

Tetrahedron Letters p. 7995 - 7998 (1995)

Update date:2022-08-05

Topics:

Authors:

Comins, Daniel L.

Saha, Jayanta K.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0040-4039(95)01665-5

The DE ring camptothecin intermediate II was prepared enantioselectively in six steps from 2-fluoropyridine using a pyridine "halogen-dance" reaction.

Full text of DOI:10.1016/0040-4039(95)01665-5

Products guided by the article

Product name:(S)-2-(2-Fluoro-3-methyl-pyridin-4-yl)-2-hydroxy-butyric acid (1R,2S)-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester

Cas No:171366-22-6

R&D Labs maybe for 171366-22-6

Leshan Kai Yada Photoelectric Technology Co., Ltd.,

website:http://www.kydmaterials.com

Contact:0833-5603116

Address:Airport road Jiajiang county, Sichuan province,China
Taizhou volsen chemical Co., Ltd

website:http://www.volsenchem.com

Contact:+86-576-88869393

Address:Jiaojiang District, Taizhou, Zhejiang, China.
Evershine Chemical CO Ltd

Contact:+86-571-87010026

Address:202, Zhenhua Road,
Shandong Zhongcheng Barium Salt Co., Ltd

Contact:+86-15725732638

Address:No.29 baoxi road, hi-tech zone, zibo, shandong
Hefei TNJ chemical industry co.,ltd

website:https://www.tnjchem.com

Contact:+86-551-65418695

Address:B911 Xincheng Business Center, Qianshan Road, Hefei Anhui China

Relevant to this article

Intramolecular 1,3-dipolar cycloaddition of transient enantiomerically pure oxaalkenyl nitrones

Doi:10.1055/s-1995-4060
(1995)
Method for Highly Enantioselective Ligation of Two Chiral C(sp³) Stereocenters

Doi:10.1021/jacs.7b07366
(2017)
Poly(pyrazol-1-ylmethyl)benzenes: New Multidentate Ligands

Doi:10.1071/CH9951587
(1995)
Tetraethylammonium (2-Thioxo-1,3-dithiole-4,5-dithiolato-S⁴,S⁵)triphenylphosphinecopper(I)

Doi:10.1107/S0108270195002885
(1995)
Metabolic products of fungi. XXVI. Synthesis of racemic ustilaginoidin A and its related compounds. (1). Synthesis of 2.2',4.4',5.5',7.7'-octamethoxy-1.1'-binaphthalene (=product A octamethyl ether).

Doi:10.1248/cpb.15.1765
(1967)
Enantioselective alkylation of aldehydes catalyzed by new chiral diselenides

Doi:10.1016/0040-4039(95)01668-8
(1995)

Article Doi