Highly stereoselective reduction of α-keto esters: Utility of cis-1-arylsulfonamido-2-indanols as chiral auxiliaries

DOI: 10.1016/00404-0399(50)1385U-

Source and publish data:

Tetrahedron Letters p. 6811 - 6814 (1995)

Update date:2022-07-30

Topics:

Authors:

Ghosh Ghosh

Ghosh, Arun K.

Chen Chen

Yan, Chen

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Article abstract of DOI:10.1016/00404-0399(50)1385U-

The reduction of α-keto esters bearing cis-1-arylsulfonamide-2-indanol derivatives proceeded with high diastereoselectivities providing the corresponding α-hydroxy esters in excellent yields. The chiral auxiliary group is removed under mild basic conditions and recovered.

Full text of DOI:10.1016/00404-0399(50)1385U-

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