
Tetrahedron p. 10343 - 10360 (1995)
Update date:2022-08-05
Topics:
Guanti, Giuseppe
Banfi, Luca
Riva, Renata
The reduction with various hydrides and the addition of some Grignard reagents and aklyl lithiums to various protected 1-hydroxy-2-phenylalkan-3-ones furnished respectively the corresponding secondary and tertiary alcohols with a diastereoselectivity from good to excellent.Both processes were stereoconservative, no racemization being observed.
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(1995)