Tetrahedron Asymmetry p. 1557 - 1560 (1995)
Update date:2022-08-03
Topics:
Harwood, L. M.
Lilley, I. A.
The preparation and subsequent diastereoselective 1,3- dipolar cycloaddition of E-carboethoxy-substituted azomethine ylids derived by condensating 5-(S)-phenylmorpholinone (1) with ethyl glyoxalate is described.Removal of the chiral template furnishes enantiomerically pure pyrrolidine-2,5-dicarboxylate derivatives.
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