Synthesis of Optically Active 1-t-Butyl-4-ethylidenecyclohexane via CO2-Elimination from a Spirofused β-Lactone

Article abstract of DOI:10.1016/0040-4039(95)01596-A

(R)-1-t-Butyl-4-ethylidene cyclohexane ((R)-1) is prepared with >98percent ee from 4-t-butylcyclohexane carboxylic acid via the optically active β-lactone 10. - Key Words: (R)-1-t-Butyl-4-ethylidenecyclohexane, diastereoselectivity, chiral auxiliary, imid