5-Acetyl-6-amino-4-methylthio-2-phenylpyrimidines and its use in the synthesis of functionalized pyridopyrimidines and pyrimidopyrimidines

Article abstract of DOI:10.1007/BF00700904

Schemes for the synthesis of MeS-substituted pyrido<2,3-d>pyrimidin-5-one, pyrimido<4,5-d>pyrimidine, and 4-methylenepyrimido<4,5-d>pyrimidin-2-one based on 5-acetyl-6-amino-4-methylthio-2-phenylpyrimidine, which was prepared from the adduct of benzoyl isothiocyanate with acetylketene N-benzoylaminal, were suggested. - Keywords: 5-acetyl-6-amino-4-methylthio-2-phenylpyrimidine; pyrido<2,3-d>pyriminin-5-one; pyrimido<4,5-d>pyrimidine; 4-methylenepyrimido<4,5-d>pyrimidin-2-one; acetylketene aminal; benzoyl isothiocyanate; phenyl isocyanate; dimethylformamide dimethylacetal; dimethylacetamide dimethylacetal.