
Journal of Medicinal Chemistry p. 1582 - 1592 (1995)
Update date:2022-09-26
Topics:
Hoekstra
Beavers
Andrade-Gordon
Evangelisto
Keane
Press
Tomko
Fan
Kloczewiak
Mayo
Durkin
Liotta
Two series of nonpeptide turn mimetics were designed by analysis of the solution NMR structure of the 385-411 sequence of the γ-chain of fibrinogen. These compounds, based on the KQAGD (Lys-Gln-Ala-Gly-Asp, 406-410) sequence, were synthesized and studied
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