Efficient Synthesis of O-(2-Acetamido-2-deoxy-β-D-glucopyranosyl)-Ser/Thr Building Blocks for SPPS of O-GlcNAc Glycopeptides

Article abstract of DOI:10.1016/0040-4039(95)01941-A

Suitably protected building blocks for solid-phase synthesis of β-O-GlcNAc glycopeptides, N^α-Fmoc-Ser(Ac3-β-D-GlcNAc)-OPfp 10 and N^α-Fmoc-Thr(Ac3-β-D-GlcNAc)-OPfp 11 have been synthesized by stereoselective glycosylation of N^α