Syntheses of biphenyl analogues of AP7, a new class of competitive N-methyl-D-aspartate (NMDA) receptor antagonists

DOI: 10.1002/hlca.19950780810

Source and publish data:

Helvetica Chimica Acta p. 2026 - 2035 (1995)

Update date:2022-07-29

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Authors:

Muller Muller

Kipfer Kipfer

Lowe Lowe

Urwyler Urwyler

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Article abstract of DOI:10.1002/hlca.19950780810

Affinities for the NMDA receptor were measured ([³H]CGP-39653 binding assay) and competitive NMDA antagonistic potencies determined in a functional test (rat neocortical slice preparation). Structure-activity relationships show that attachment

Full text of DOI:10.1002/hlca.19950780810

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