Palladium-catalyzed reaction of 1-aza-5-germa-5-organobicyclo[3.3.3]undecane with aryl bromide

Article abstract of DOI:10.1016/0022-328X(95)05840-L

Successive treatment of triallylamine with zirconocene chloride hydride and germanium tetrachloride affords 1-aza-5-germa-5-chlorobicyclo[3.3.3]undecane, which is converted to the 5-organo derivatives by the reaction with Grignard or lithium reagents. The organo groups showed higher reactivities toward Stille-type coupling than the corresponding organotributylgermanes.