1-bromo-3,5-bis(trifhioromethyl)benzene: A versatile starting material for organometallic synthesis

Article abstract of DOI:10.1002/cber.19961290219

1-Bromo-3,5-bis(trifluoromethyl)benzene (1) can be selectively prepared by treatment of 1,3-bis(fluorornethyl)benzene with N,N′-dibromo-5,5-dimethylhydantoin in strongly acidic media. A number of synthetically useful reactions via 3,5bis{trifluoromethyl)phenylmagnesium, -lithium, and -copper intermediates were accomplished. VCH Verlagsgesellschaft mbH, , 1996.