A synthesis of 2-acyl-3-hydroxythiophenes

Article abstract of DOI:10.1080/00397919608003715

2-Acyl-3-hydroxythiophenes have been made by the reaction of the anion of a mercaptoketone with dimethyl acetylenedicarboxylate to give a hydroxythiophene ester which is then hydrolysed and decarboxylated.

Full text of DOI:10.1080/00397919608003715

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Synthetic Communications:
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A Synthesis of 2-ACYL- 3-
Hydroxythiophenes
Yolante Z. Adamczewska a , John M. Barker a ,
Patrick R. Huddleston a & Michael L. Wood a
a Dept. of Chemistry and Physics, The
Nottingham Trent University, Clifton Lane,
Nottingham, NGll 8NS, UK
Published online: 21 Aug 2006.
To cite this article: Yolante Z. Adamczewska , John M. Barker , Patrick
R. Huddleston & Michael L. Wood (1996): A Synthesis of 2-ACYL- 3-
Hydroxythiophenes, Synthetic Communications: An International Journal for
Rapid Communication of Synthetic Organic Chemistry, 26:6, 1083-1096
To link to this article: http://dx.doi.org/10.1080/00397919608003715
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