A simple strategy for spirocyclopentannulation of cyclic ketones. Formal total synthesis of (±)-acorone

Article abstract of DOI:10.1016/0040-4039(96)00109-8

A general and simple methodology for spirocyclopentannulation of cyclic ketones (or 4,4-disubstituted cyclopentenones from acyclic ketones) and its application in the synthesis of the spirodienone 7 via a prochiral precursor constituting a formal total synthesis of (±)-acorone (6), are described.