Journal of the Chemical Society. Perkin transactions I p. 475 - 483 (1996)
Update date:2022-08-03
Topics:
Aitken, R. Alan
Cooper, Harris R.
Mehrotra, Amit P.
A series of 11 amino acid-derived stabilised ylides 12-14 and 16 have been prepared and characterised. In one case, for compound 17, an X-ray structure determination supports formulation of the compounds as phosphonium enolates. Flash vacuum pyrolysis (FVP) of 12 and 13 at 500°C results in loss of R23PO between the ylide function and one carbonyl of the phthalimido group to give products characterised spectroscopically as the pyrroloisoindolediones 18. The identity of these is also supported by the results of 13C and 15N labelling experiments, but owing to their high reactivity complete separation from the phosphine oxide was not generally possible even when Bu3PO rather than Ph3PO was involved. Chromatographic purification of 29, similarly produced by FVP of 14, led to partial hydrolysis, rearrangement and decarboxylation to give 30. FVP of 12 at 750°C gave the 1-unsubstituted pyrroloisoindolediones 19 in two cases.
View MoreHunan Dinuo Pharmaceutical Co.,Ltd.
Contact:86-731-88280100*8561
Address:Bio-pharmaceutical industrial park, Liuyang, Hunan, China
Contact:13813902930 025-52714267
Address:20 Fengji Road, Yuhua Economic Development Zone, Nanjing, Jiangsu, P. R. China
Tianjin Jingye Fine Chemicals Co., Ltd.
Contact:+86-15722078107; +86-22-26911407
Address:Bohua Fine Chemicals Base of Petrochemical Industry Park, Nanhuan Road, Dagang District, Tianjin, 300271, P. R. China
Lanling Hongchuang Flame Retardant Co., Ltd.
Contact:+86-531-68858132
Address:East Huafeichang Road, Cangshan County, Linyi, Shandong, China (Mainland)
Shanghai KFSL Pharmaceutical Technology Co.,Ltd.
Contact:+86-21-39971718
Address:859 jiadingchengliu shanghai
Doi:10.1016/S0040-4020(01)98198-0
(1971)Doi:10.1021/jo0353886
(2004)Doi:10.1021/om9905916
(1999)Doi:10.1039/c5cc07252b
(2015)Doi:10.1016/0223-5234(96)80446-6
(1996)Doi:10.1021/om950813+
(1996)
