Tetrahedron Letters p. 1795 - 1798 (1996)
Update date:2022-08-05
Topics:
Ito, Hisanaka
Imai, Nobuyuki
Tanikawa, Shin
Kobayashi, Susumu
Total synthesis of curacin A, a novel antimitotic antiproliferative antibiotic, was achieved by the connection of C1-C7, C8-C17, and C18-C22 segments. Enantioselective preparation of each segments were accomplished by asymmetric allylation, chiral synthon method, and asymmetric hydrolysis by using pig liver esterase, respectively.
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Doi:10.1248/cpb.44.725
(1996)Doi:10.1080/00397919608003541
(1996)Doi:10.1016/0968-0896(95)00181-6
(1996)Doi:10.1016/0040-4039(96)00408-X
(1996)Doi:10.1039/c5ra15817f
(2015)Doi:10.1080/07328319608002131
(1996)
