Thermal removal of BOC-protecting groups during preparation of open-chain polyamines

Article abstract of DOI:10.1080/00397919608003822

Per-N-tosylated 3,8-diaza-1,10-decanediamine (9), 4,9-diaza-1,12-dodecanediamine (spermine) (10) and 3,6,9,14,17,20-hexaaza-1,22-docosanediamine (11) were prepared by treating mono-BOC-protected, per-N-tosylated 1,2-ethanediamine (5), 1,3-propanediamine (6) and triethylenetetraamine (7), respectively, with 1,4-dibromobutane and removing the BOC-protecting groups at 100-120°C.

Full text of DOI:10.1080/00397919608003822

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Synthetic Communications: An
International Journal for Rapid
Communication of Synthetic
Organic Chemistry
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Thermal Removal of Boc-
Protecting Groups During
Preparation of Open-Chain
Polyamines
Krzysztof E. Krakowiak a & Jerald S. Bradshaw b
a IBC Advanced Technologies , Inc., PO Box 98,
American Fork, UT, 84003
b Department of Chemistry and Biochemistry ,
Brigham Young University , Provo, UT, 84602
Published online: 23 Aug 2006.
To cite this article: Krzysztof E. Krakowiak & Jerald S. Bradshaw (1996) Thermal
Removal of Boc-Protecting Groups During Preparation of Open-Chain Polyamines,
Synthetic Communications: An International Journal for Rapid Communication of
Synthetic Organic Chemistry, 26:21, 3999-4004, DOI: 10.1080/00397919608003822
To link to this article: http://dx.doi.org/10.1080/00397919608003822
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