N-Phosphorylated lactams 2. Reversible phosphorylation of silyllactams

Article abstract of DOI:10.1007/BF00696723

The phosphorylation of N-trimethylsilyllactams by phosphorus(III) acid chlorides results in corresponding N-phosphinolactams in high yields. The derivatives thus obtained have been used in the synthesis of N-phosphoryl- and N-thiophosphoryllactams. The reversibility of the reaction of phosphinolactams has been established. - Keywords: N-trimethylsilyllactams; reversible phosphorylation; N-phosphoryllactams, synthesis.